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The safety profile of retatrutide was similar to other incretin-based medications

Conclusions Significant weight regain occurred 8 weeks after discontinuation of AOMs and was sustained through 20 weeks

Am J Dermatopathol 2014

Ivy et al (20) verified a reduction in total time to complete a reference load equal to one hour of cycling, at 70% of the maximum load

A peptide batch with 95% purity contains 5% impurities

Verdict at a Glance Retatrutide demonstrated greater weight loss than survodutide in their respective Phase 2 trials (24.2% vs 18.7%), likely driven by its unique triple-agonist mechanism that adds GIP receptor activation